GTF2H2 anticorps

N° du produit ABIN7126497

L’anticorps anti-GTF2H2 Monoclonal Souris est utilisé pour la détection de GTF2H2 dans des échantillons de Humain. Il a été validé pour IF et FACS.

Aperçu rapide pour GTF2H2 anticorps (ABIN7126497)

Antigène: GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GTF2H2 est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-GTF2H2-1B9

Détail du produit anti-GTF2H2 anticorps

Fonction: GTF2H2 / BTF2 / TFIIH Basal Transcription Factor Antibody

Specificité: Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFII. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and Mat1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.

Réactivité croisée (Details): Human

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human GTF2H2 protein

Isotype: IgG1

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or MCF7 cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur GTF2H2

Antigène: GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))

Autre désignation: GTF2H2

Sujet:

Basic transcription factor 2 44 kDa subunit, BTF2, BTF2-p44, BTF2P44, General transcription factor IIH, polypeptide 2, 44 kDa, T-BTF2P44, TFIIH basal transcription factor complex p44 subunit

HeLa or MCF7 cells.

Poids moléculaire: 44kDa

ID gène: 2966, 607501

UniProt: Q13888

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling