GTF2H2 anticorps

N° du produit ABIN930961

Cet anticorps Souris Monoclonal détecte spécifiquement GTF2H2 dans DB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour GTF2H2 anticorps (ABIN930961)

Antigène: GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GTF2H2 est non-conjugé

Application: Dot Blot (DB)

Clone: GTF2F6A10

Détail du produit anti-GTF2H2 anticorps

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogène: GTF2 H2 antibody was raised in mouse using recombinant Human General Transcription Factor Iih, Polypeptide 2, 42 da

Isotype: IgG1

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: GTF2 H2 antibody in PBS (3.0 mM KCl,1.5 mM KH2 O4, 140 mM NaCl, 8.0 mM Na2 P04 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Détails sur GTF2H2

Antigène: GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))

Autre désignation: GTF2H2

Sujet: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. This gene encodes the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Synonyms: Monoclonal GTF2H2 antibody, Anti-GTF2H2 antibody, General transcription factor IIH subunit 2 antibody, BTF2 antibody, TFIIH antibody, BTF2P44 antibody, T-BTF2P44 antibody.

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling