APOB anticorps (AA 592-689)

N° du produit ABIN7126529

Cet anticorps Souris Monoclonal détecte spécifiquement APOB dans IHC (f). Il présente une réactivité envers Humain.

Aperçu rapide pour APOB anticorps (AA 592-689) (ABIN7126529)

Antigène: APOB (Apolipoprotein B (APOB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp APOB est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Détail du produit anti-APOB anticorps

Épitope: AA 592-689

Specificité: Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated byAPOBEC1 (also designated human (or rat) small intestinal apolipoprotein BmRNA editing protein, HEPR or REPR) in hepatic cells to achieve a steadystate proportion of edited and unedited RNA molecules. Two forms of apoBare known to circulate in the plasma of mammals. ApoB-100 is a proteinprimarily synthesized in the liver as a structural component of very low densitylipoprotein particles. A truncated form of apoB-100, apoB-48, is synthesizedin the small intestine and contains the amino-terminal 2,152 amino acids ofthe larger protein. This organ-specific partitioning of apoB production is theresultof RNA editing of a common apoB gene.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Human recombinant APOB protein fragment (around aa592-689) (exact sequence is proprietary)

Isotype: IgG2b

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human liver or kidney tissue.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur APOB

Antigène: APOB (Apolipoprotein B (APOB))

Autre désignation: APOB

Sujet: ApoB 100, ApoB 48, Apolipoprotein B (including Ag(x) antigen), Apolipoprotein B 100, Apolipoprotein B 48, Apolipoprotein B, FLDB, LDLCQ4,Apolipoprotein B /APOB
Cellular localisation: Cytoplasm. Secreted.

Poids moléculaire: 512kDa

ID gène: 338, 120759

UniProt: P04114

Pathways: Lipid Metabolism