Recombinant Interferon gamma anticorps

N° du produit ABIN7126540

Détail du produit anti-Interferon gamma anticorps

Antigène: Interferon gamma (IFNG)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Interferon gamma est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: Recognizes a protein of 20-25 kDa, identified as human interferon. This MAb is specific to human IFN-i³ and recognizes both recombinant and native human IFN-gamma. T lymphocytes and NK cells mainly produce IFN-i³. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFN-i±/i² (type I interferon).

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human IFNG protein

Isotype: IgG

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: PMA stimulated human peripheral blood mononuclear cells. Renal or testicular carcinoma.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur Interferon gamma

Antigène: Interferon gamma (IFNG)

Autre désignation: IFNG (IFNG Produits)

Synonymes: anticorps IFG, anticorps IFI, anticorps IFN-g, anticorps Ifg, anticorps IFNG2, anticorps IFN-gamma, anticorps IFN-G, anticorps IFNG, anticorps IFNgamma, anticorps TCRalpha, anticorps INF-G, anticorps ifng, anticorps interferon gamma, anticorps interferon, gamma 1-2, anticorps IFNG, anticorps Ifng, anticorps ifng1-2

Sujet: AMCF1, Beta thromboglobulin like protein, CXC chemokine ligand 8 (CXCL8), Emoctakin, Granulocyte chemotactic protein 1 (GCP1), IFG, IFI, IFN Immune, Interleukin 8, LECT, LUCT, Lymphocyte derived neutrophil activating factor, LYNAP, Macrophage Activating Factor (MAF), Monocyte derived neutrophil activating protein (MONAP), Monocyte derived neutrophil chemotactic factor (MDNCF), Neutrophil activating factor (NAF), Neutrophil activating peptide 1 (NAP1), Neutrophil activating protein 1 (NAP1), SCYB8, T cell chemotactic factor, T Cell Interferon,Interferon gamma (IFNG)
Cellular localisation: Cytoplasmic & Cell Surface

Poids moléculaire: 20-25kDa

ID gène: 3458, 856

UniProt: P01579

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy