IL3RA anticorps (AA 26-171)

N° du produit ABIN7126575

Détail du produit anti-IL3RA anticorps

Antigène: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Épitope: AA 26-171

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL3RA est non-conjugé

Application: ELISA, Coating (Coat)

Specificité: CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant human IL3RA protein fragment (around aa 26-171) (exact sequence is proprietary)

Isotype: IgG2a

Information d'application

Indications d'application:

Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), ,Optimal dilution for a specific application should be determined.

Positive_Control: THP-1, RPMI-8226 or HDLM-2 cells. Tonsil, Lymph Node or Stomach

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur IL3RA

Antigène: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Autre désignation: IL3RA (IL3RA Produits)

Synonymes: anticorps CD123, anticorps IL3R, anticorps IL3RAY, anticorps IL3RX, anticorps IL3RY, anticorps hIL-3Ra, anticorps CDw123, anticorps SUT-1, anticorps Cyrl, anticorps interleukin 3 receptor subunit alpha, anticorps interleukin 3 receptor, alpha chain, anticorps IL3RA, anticorps Il3ra

Sujet: CD123, hIL3Ra, IL-3R-alpha, IL-3RA, IL3RAX, IL3RAY, IL3RX, IL3RY, Interleukin-3 Receptor, alpha, Interleukin3 receptor, Interleukin3 receptor, Y-chromosomal,IL3RA / CD123 (Acute Myeloid Leukemia Marker)
Cellular localisation: Cell surface and cytoplasm.

Poids moléculaire: ~70kDa

ID gène: 3563, 632790

UniProt: P26951

Pathways: Signalistation JAK/STAT