PSMD4/ASF anticorps
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- Antigène Voir toutes PSMD4/ASF (Psmd4) Anticorps
- PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PSMD4/ASF est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- In eukaryotic cells, selective breakdown of cellular proteins is ensured by two distinct pathways. First, appropriate proteins are tagged for degradation by ubiquitination. Second, these multiubiquitinated proteins are degraded by the highly selective 26S Proteasome protein-destroying machinery. At specific stages of development, embryo- and tissue-specific components of the 26S Proteasome are formed, which are termed Rpn10a through Rpn10e, or alternatively pUb-R2 through pUb-R5. All members of this family can be generated by a single Rpn10 gene by developmentally regulated alternative splicing. The pUb-R2 subunit, originally identified as S5a (also designated antisecretory factor and multiubiquitin chain binding protein) is ubiquitously expressed and may perform proteolysis constitutively in a wide variety of cells. pUb-R4 and pUb-R5 may have embryo- or tissue-specific expression and may play specialized roles in early embryonic development.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant full-length human PSMD4protein
- Isotype
- IgG2b
- Top Product
- Discover our top product Psmd4 Anticorps primaire
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- Indications d'application
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Known_Application: Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: Jurkat or HepG2 cells. Liver tissue lysate. Human liver, tonsil or kidney.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))
- Autre désignation
- PSMD4 (Psmd4 Produits)
- Synonymes
- anticorps af-1, anticorps mcb1, anticorps pub-r5, anticorps rpn10, anticorps PSMD4, anticorps DDBDRAFT_0202512, anticorps DDBDRAFT_0232981, anticorps DDB_0202512, anticorps DDB_0232981, anticorps AF, anticorps AF-1, anticorps ASF, anticorps MCB1, anticorps Rpn10, anticorps S5A, anticorps pUB-R5, anticorps xrpn10c, anticorps Af1, anticorps Mcb1, anticorps angiocidin, anticorps im:6912672, anticorps psmd4, anticorps wu:fc68c04, anticorps zgc:110247, anticorps proteasome 26S subunit, non-ATPase 4, anticorps 26S proteasome non-ATPase regulatory subunit 4, anticorps 26s proteasome non-atpase regulatory subunit 4 (26s proteasomeregulatory subunit s5a), anticorps proteasome 26S subunit, non-ATPase 4 L homeolog, anticorps proteasome (prosome, macropain) 26S subunit, non-ATPase, 4, anticorps proteasome 26S subunit, non-ATPase 4b, anticorps psmd4, anticorps PSMD4, anticorps LOC100194679, anticorps psmD4, anticorps LOC100283637, anticorps Smp_000740.1, anticorps psmd4.L, anticorps Psmd4, anticorps psmd4b
- Sujet
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26S proteasome non-ATPase regulatory subunit 4, 26S proteasome regulatory subunit RPN10, 26S proteasome regulatory subunit S5A, AF, AF-1,26S proteasome non-ATPase regulatory subunit 4
Cellular localisation: Nucleus and cytoplasm. - Poids moléculaire
- 50kDa
- ID gène
- 5710, 505059
- UniProt
- P55036
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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