Recombinant CD47 anticorps (AA 18-135)
Aperçu rapide pour Recombinant CD47 anticorps (AA 18-135) (ABIN7127215)
Antigène
Voir toutes CD47 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 18-135
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Specificité
- This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.
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Réactivité croisée (Details)
- Human.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogène
- A recombinant fragment (around aa 18-135) of human CD47 protein (exact sequence is proprietary)
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Isotype
- IgG
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Indications d'application
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Known_Application: ELISA (For coating, order antibody without BSA), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human placenta, brain or ovarian tumors (IHC).
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Date de péremption
- 24 months
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- CD47
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Autre désignation
- CD47
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Sujet
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Antigenic Surface Determinant Protein OA3, IAP, Integrin Associated Protein, Integrin Associated Signal Transducer, MER6, OA3, Protein MER6, Rh Related Antigen,CD47 / IAP (Integrin Associated Protein)
Cellular localisation: Cell Surface -
Poids moléculaire
- ~50kDa
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ID gène
- 961, 446414
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UniProt
- Q08722
Antigène
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