Recombinant Angiopoietin 2 anticorps

N° du produit ABIN7127339

Cet anticorps Lapin Monoclonal détecte spécifiquement Angiopoietin 2 dans IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Recombinant Angiopoietin 2 anticorps (ABIN7127339)

Antigène: Angiopoietin 2 (ANGPT2)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Angiopoietin 2 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Clone: 1F10

Détail du produit anti-Angiopoietin 2 anticorps

Fonction: ANGPT2 Recombinant Monoclonal Antibody

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human Angiopoietin 2

Isotype: IgG

Information d'application

Indications d'application: IHC:1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Angiopoietin 2

Antigène: Angiopoietin 2 (ANGPT2)

Autre désignation: ANGPT2

Sujet:

Background: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

Aliases: Angiopoietin-2 (ANG-2), ANGPT2

UniProt: O15123

Pathways: Signalisation RTK