Recombinant CD47 anticorps
Aperçu rapide pour Recombinant CD47 anticorps (ABIN7127404)
Antigène
Voir toutes CD47 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- CD47 Recombinant Monoclonal Antibody
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Purification
- Affinity-chromatography
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Immunogène
- A synthesized peptide derived from human CD47
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Isotype
- IgG
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Indications d'application
- WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CD47
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Autre désignation
- CD47
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Sujet
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Background: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
Aliases: Leukocyte surface antigen CD47 (Antigenic surface determinant protein OA3) (Integrin-associated protein) (IAP) (Protein MER6) (CD antigen CD47), CD47, MER6
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UniProt
- Q08722
Antigène
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