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Recombinant FAS anticorps

FAS Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Monoclonal 2B6 unconjugated Recombinant Antibody
N° du produit ABIN7127483
  • Antigène Voir toutes FAS Anticorps
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    • 219
    • 67
    • 66
    • 19
    • 9
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 154
    • 99
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 155
    • 108
    • 1
    Monoclonal
    Conjugué
    • 122
    • 29
    • 25
    • 12
    • 11
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FAS est non-conjugé
    Application
    • 160
    • 127
    • 72
    • 66
    • 39
    • 34
    • 30
    • 26
    • 26
    • 18
    • 16
    • 12
    • 8
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
     Réactivité croisée
    Humain
    Purification
    Affinity-chromatography
    Immunogène
    A synthesized peptide derived from human Fas
    Clone
    2B6
    Isotype
    IgG
    Top Product
    Discover our top product FAS Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    Autre désignation
    FAS (FAS Produits)
    Synonymes
    anticorps ALPS1A, anticorps APO-1, anticorps APT1, anticorps CD95, anticorps FAS1, anticorps FASTM, anticorps TNFRSF6, anticorps AI196731, anticorps APO1, anticorps TNFR6, anticorps Tnfrsf6, anticorps lpr, anticorps Fas cell surface death receptor, anticorps Fas (TNF receptor superfamily member 6), anticorps FAS, anticorps Fas, anticorps fas
    Sujet

    Background: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

    Aliases: Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95), FAS, APT1 FAS1 TNFRSF6

    UniProt
    P25445
    Pathways
    Signalisation p53, Apoptose, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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