Recombinant IFNAR1 anticorps

N° du produit ABIN7127561

Cet anticorps Lapin Monoclonal détecte spécifiquement IFNAR1 dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Recombinant IFNAR1 anticorps (ABIN7127561)

Antigène: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNAR1 est non-conjugé

Application: ELISA

Clone: 1B12

Détail du produit anti-IFNAR1 anticorps

Fonction: IFNAR1 Recombinant Monoclonal Antibody

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human IFNAR1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur IFNAR1

Antigène: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Autre désignation: IFNAR1

Sujet:

Background: Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986). Functions in general as heterodimer with IFNAR2 (PubMed:7665574, PubMed:10049744, PubMed:21854986). Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (PubMed:7665574, PubMed:21854986). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity).

Aliases: Interferon alpha/beta receptor 1, IFN-R-1, IFN-alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1, IFNAR1, IFNAR

UniProt: P17181

Pathways: Signalistation JAK/STAT, Hepatitis C