Recombinant IGF2 anticorps
Aperçu rapide pour Recombinant IGF2 anticorps (ABIN7127562)
Antigène
Voir toutes IGF2 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- IGF2 Recombinant Monoclonal Antibody
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Purification
- Affinity-chromatography
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Immunogène
- A synthesized peptide derived from human IGF2
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- IGF2 (Insulin-Like Growth Factor 2 (IGF2))
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Autre désignation
- IGF2
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Sujet
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Background: The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation (By similarity). In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver (Probable). Acts as a ligand for integrin which is required for IGF2 signaling (PubMed:28873464).
Aliases: Insulin-like growth factor II, IGF-II, Somatomedin-A, T3M-11-derived growth factor, Insulin-like growth factor II, Insulin-like growth factor II Ala-25 Del, Preptin, IGF2, PP1446
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UniProt
- P01344
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Pathways
- Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation
Antigène
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