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Recombinant ISL1 anticorps

Cet anticorps anti-ISL1 est un anticorps Lapin Monoclonal détectant ISL1 dans WB et ELISA. Adapté pour Humain.
N° du produit ABIN7127581

Aperçu rapide pour Recombinant ISL1 anticorps (ABIN7127581)

Antigène

Voir toutes ISL1 Anticorps
ISL1 (ISL LIM Homeobox 1 (ISL1))

Type d'anticorp

Recombinant Antibody

Reactivité

  • 79
  • 50
  • 33
  • 8
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Humain

Hôte

  • 76
  • 11
Lapin

Clonalité

  • 64
  • 23
Monoclonal

Conjugué

  • 44
  • 6
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp ISL1 est non-conjugé

Application

  • 60
  • 32
  • 14
  • 13
  • 10
  • 8
  • 8
  • 6
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA

Clone

4F6
  •  Réactivité croisée

    Humain

    Purification

    Affinity-chromatography

    Immunogène

    A synthesized peptide derived from human Islet 1

    Isotype

    IgG
  • Indications d'application

    Recommended dilution: WB:1:500-1:5000,

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène

    ISL1 (ISL LIM Homeobox 1 (ISL1))

    Autre désignation

    ISL1

    Sujet

    Background: DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Cooperates with the transcription factor POU4F2 to achieve maximal levels of expression of RGC target genes and RGC fate specification in the developing retina. Involved in the specification of motor neurons in cooperation with LHX3 and LDB1. Binds to insulin gene enhancer sequences.

    Aliases: Insulin gene enhancer protein ISL-1 (Islet-1), ISL1

    UniProt

    P61371

    Pathways

    Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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