Recombinant EIF4E anticorps (pSer209)
Aperçu rapide pour Recombinant EIF4E anticorps (pSer209) (ABIN7127691)
Antigène
Voir toutes EIF4E AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- pSer209
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Fonction
- Phospho-EIF4E (S209) Recombinant Monoclonal Antibody
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Purification
- Affinity-chromatography
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Immunogène
- A synthesized peptide derived from human Phospho-EIF4E (S209)
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Isotype
- IgG
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Indications d'application
- WB:1:500-1:5000, IHC:1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
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Autre désignation
- EIF4E
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Sujet
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Background: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
Aliases: Eukaryotic translation initiation factor 4E, eIF-4E, eIF4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein, EIF4E, EIF4EL1, EIF4F
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UniProt
- P06730
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Pathways
- BCR Signaling
Antigène
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