Recombinant LAT anticorps (pTyr191)

N° du produit ABIN7127705

Cet anticorps Lapin Monoclonal détecte spécifiquement LAT dans WB, ELISA, IHC, IP et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour Recombinant LAT anticorps (pTyr191) (ABIN7127705)

Antigène: LAT (Linker For Activation of T Cells (LAT))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp LAT est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: 2E4

Détail du produit anti-LAT anticorps

Épitope: pTyr191

Fonction: Phospho-LAT (Y191) Recombinant Monoclonal Antibody

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human Phospho-LAT (Y191)

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur LAT

Antigène: LAT (Linker For Activation of T Cells (LAT))

Autre désignation: LAT

Sujet:

Background: Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

Aliases: Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, pp36, p36-38, LAT

UniProt: O43561

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway