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Recombinant LAT anticorps (pTyr191)

LAT Reactivité: Humain WB, ELISA, IHC, IP, IF Hôte: Lapin Monoclonal 2E4 unconjugated Recombinant Antibody
N° du produit ABIN7127705
  • Antigène Voir toutes LAT Anticorps
    LAT (Linker For Activation of T Cells (LAT))
    Type d'anticorp
    Recombinant Antibody
    Épitope
    • 19
    • 15
    • 15
    • 8
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr191
    Reactivité
    • 133
    • 59
    • 41
    • 1
    • 1
    Humain
    Hôte
    • 115
    • 18
    • 2
    • 1
    Lapin
    Clonalité
    • 118
    • 18
    Monoclonal
    Conjugué
    • 64
    • 8
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    Cet anticorp LAT est non-conjugé
    Application
    • 73
    • 40
    • 39
    • 39
    • 17
    • 10
    • 10
    • 9
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
     Réactivité croisée
    Humain
    Purification
    Affinity-chromatography
    Immunogène
    A synthesized peptide derived from human Phospho-LAT (Y191)
    Clone
    2E4
    Isotype
    IgG
    Top Product
    Discover our top product LAT Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    LAT (Linker For Activation of T Cells (LAT))
    Autre désignation
    LAT (LAT Produits)
    Synonymes
    anticorps LAT, anticorps lat, anticorps LAT1, anticorps pp36, anticorps linker for activation of T-cells, anticorps linker for activation of T cells, anticorps LAT, anticorps lat, anticorps Lat
    Sujet

    Background: Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

    Aliases: Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, pp36, p36-38, LAT

    UniProt
    O43561
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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