Recombinant TINF2 anticorps
Aperçu rapide pour Recombinant TINF2 anticorps (ABIN7127845)
Antigène
Voir toutes TINF2 (TIN2) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Réactivité croisée
- Humain, Souris, Rat
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Purification
- Affinity-chromatography
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Immunogène
- A synthesized peptide derived from human Tin2
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Isotype
- IgG
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Indications d'application
- Recommended dilution: WB:1:500-1:5000,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))
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Autre désignation
- TINF2
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Sujet
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Background: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.
Aliases: TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2), TINF2, TIN2
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UniProt
- Q9BSI4
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Pathways
- Cycle Cellulaire, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process
Antigène
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