MDM4-binding Protein anticorps (pSer367)

N° du produit ABIN7138576

Cet anticorps anti-MDM4-binding Protein est un anticorps Lapin Polyclonal détectant MDM4-binding Protein dans WB, ELISA et IHC. Adapté pour Humain.

Aperçu rapide pour MDM4-binding Protein anticorps (pSer367) (ABIN7138576)

Antigène: MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MDM4-binding Protein est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-MDM4-binding Protein anticorps

Épitope: pSer367

Fonction: Phospho-MDM4 (Ser367) Antibody

Réactivité croisée: Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of serine 367 (T-I-S(p)-A-P) derived from Human MDM4.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MDM4-binding Protein

Antigène: MDM4-binding Protein (MDM4) (Mdm4-binding Protein (MDM4))

Autre désignation: MDM4

Sujet:

Background: Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.

Aliases: DKFZp781B1423 antibody, Double minute 4 antibody, Double minute 4 human homolog of p53 binding protein antibody, Double minute 4 protein antibody, HDMX antibody, MDM 4 antibody, Mdm2 like p53 binding protein antibody, Mdm2-like p53-binding protein antibody, MDM4 antibody, Mdm4 p53 binding protein homolog mouse antibody, Mdm4 protein antibody, MDM4 related protein 1 antibody, Mdm4 transformed 3T3 cell double minute 4 antibody, Mdm4 transformed 3T3 cell double minute 4 p53 binding protein antibody, Mdm4 transformed 3T3 cell double minute 4 p53 binding protein mouse antibody, MDM4_HUMAN antibody, Mdmx protein antibody, MGC132766 antibody, Mouse double minute 4 homolog antibody, Mouse double minute 4 human homolog of p53 binding protein antibody, MRP 1 antibody, MRP1 antibody, p53 binding protein antibody, p53 BINDING PROTEIN MDM4 antibody, p53-binding protein Mdm4 antibody, Protein Mdm4 antibody, Protein Mdmx antibody

UniProt: O15151

Pathways: Cycle Cellulaire