Connexin 43/GJA1 anticorps (pSer368)

N° du produit ABIN7138577

Cet anticorps Lapin Polyclonal détecte spécifiquement Connexin 43/GJA1 dans WB, IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Connexin 43/GJA1 anticorps (pSer368) (ABIN7138577)

Antigène: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Connexin 43/GJA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Connexin 43/GJA1 anticorps

Épitope: pSer368

Fonction: Phospho-GJA1 (Ser368) Antibody

Réactivité croisée: Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of serine 368(R-A-S(p)-S-R) derived from Human Connexin 43.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Connexin 43/GJA1

Antigène: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Autre désignation: GJA1

Sujet:

Background:

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.

Joell L. Solan1, et al. (2003) Cell Science 116: 2203-2211
Satoshi Matsushita, et al. (2006) Histochemistry and Cytochemistry 54 (3): 343-353,
Xiaoyong Bao, et al. (2004) Cell Physiol 286: C647-C654
W. E. I. Li, et al.(1998) European Journal of Neuroscience 10: 2444
 

Aliases: Connexin 43 antibody; Connexin-43 antibody; Cx 43 antibody; Cx43 antibody; CXA1_HUMAN antibody; DFNB38 antibody; Gap junction 43 kDa heart protein antibody; Gap junction alpha-1 protein antibody; Gap junction protein alpha 1 43kDa (connexin 43) antibody; Gap junction protein alpha 1 43kDa antibody; Gap junction protein alpha like antibody; GJA 1 antibody; Gja1 antibody; GJAL antibody; ODD antibody; ODDD antibody; ODOD antibody; SDTY3 antibody

UniProt: P17302

Pathways: Signalisation MAPK, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization