ERBB3 anticorps (pTyr1328)

N° du produit ABIN7138931

Cet anticorps Lapin Polyclonal détecte spécifiquement ERBB3 dans WB, ELISA, IHC et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour ERBB3 anticorps (pTyr1328) (ABIN7138931)

Antigène: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERBB3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-ERBB3 anticorps

Épitope: pTyr1328

Fonction: Phospho-ERBB3 (Tyr1328) Antibody

Réactivité croisée: Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of tyrosine 1328 (P-D-Y(p)-W-H) derived from Human Her3/ErbB3.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ERBB3

Antigène: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Autre désignation: ERBB3

Sujet:

Background: Binds and is activated by neuregulins and NTAK.

Holbro, T. et al. (2003) Proc. Natl. Acad. Sci. USA 100, 8933-8938.
Kobayashi, M. et al. (2003) Oncogene 22, 1294-1301.
Kim, H.H. et al. (1994) J. Biol. Chem. 269, 24747-24755.
Yarden, Y. and Sliwkowski, M.X. (2001) Nature Rev. Mol. Cell. Biol. 2, 127-137.

Aliases: c erbB 3 antibody, c erbB3 antibody, Erb b2 receptor tyrosine kinase 3 antibody, ErbB 3 antibody, ERBB3 antibody, ERBB3 protein antibody, erbB3 S antibody, ERBB3_HUMAN antibody, Glial growth factor receptor antibody, HER 3 antibody, HER3 antibody, Human epidermal growth factor receptor 3 antibody, LCCS2 antibody, MDA BF 1 antibody, MGC88033 antibody, p180 ErbB3 antibody, p45 sErbB3 antibody, p85 sErbB3 antibody, proto-oncogene-like protein c ErbB 3 antibody, proto-oncogene-like protein c ErbB3 antibody, Proto-oncogene-like protein c-ErbB-3 antibody, Receptor tyrosine protein kinase erbB 3 antibody, Receptor tyrosine protein kinase erbB3 antibody, Receptor tyrosine-protein kinase erbB-3 antibody, Tyrosine kinase type cell surface receptor HER3 antibody, Tyrosine kinase-type cell surface receptor HER3 antibody, v erb b2 avian erythroblastic leukemia viral oncogene homolog 3 antibody, v erb b2 erythroblastic leukemia viral oncogene homolog 3 (avian) antibody, v erb b2 erythroblastic leukemia viral oncogene homolog 3 antibody

UniProt: P21860

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway