Caveolin 2 anticorps (pTyr27)

N° du produit ABIN7138965

L’anticorps Lapin Polyclonal anti-Caveolin 2 a été validé pour WB et ELISA. Il convient pour détecter Caveolin 2 dans des échantillons de Humain.

Aperçu rapide pour Caveolin 2 anticorps (pTyr27) (ABIN7138965)

Antigène: Caveolin 2 (CAV2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caveolin 2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Caveolin 2 anticorps

Épitope: pTyr27

Fonction: Phospho-CAV2 (Tyr27) Antibody

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of tyrosine 27 (L-E-Y(p)-A-D) derived from Human Caveolin 2.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Caveolin 2

Antigène: Caveolin 2 (CAV2)

Autre désignation: CAV2

Sujet:

Background:

The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.

Scherer P.E., Proc. Natl. Acad. Sci. U.S.A. 93:131-135(1996).
Scherer P.E., J. Biol. Chem. 272:29337-29346(1997).
Engelman J.A., FEBS Lett. 448:221-230(1999).

Aliases: CAV antibody, CAV2 antibody, CAV2_HUMAN antibody, Caveolae protein 20 kD antibody, Caveolin 2 antibody, Caveolin 2 isoform a and b antibody, Caveolin-2 antibody, MGC12294 antibody, OTTHUMP00000025032 antibody, OTTHUMP00000195982 antibody

UniProt: P51636

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development