CSF1R anticorps (pTyr561)

N° du produit ABIN7139026

Cet anticorps anti-CSF1R est un anticorps Lapin Polyclonal détectant CSF1R dans WB, ELISA et IHC. Adapté pour Humain.

Aperçu rapide pour CSF1R anticorps (pTyr561) (ABIN7139026)

Antigène: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CSF1R est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-CSF1R anticorps

Épitope: pTyr561

Fonction: Phospho-CSF1R (Tyr561) Antibody

Réactivité croisée: Souris

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of tyrosine 561 (N-S-Y(p)-T-F) derived from Human CSFR .

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CSF1R

Antigène: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Autre désignation: CSF1R

Sujet:

Background:

Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development.

Hampe A., Oncogene Res. 4:9-17(1989).
Andre C., Genomics 39:216-226(1997).
Liu T., J. Proteome Res. 4:2070-2080(2005).

Aliases: C FMS antibody, CD 115 antibody, CD115 antibody, CD115 antigen antibody, CFMS antibody, Colony stimulating factor 1 receptor antibody, Colony stimulating factor I receptor antibody, CSF 1 R antibody, CSF 1R antibody, CSF-1 receptor antibody, CSF-1-R antibody, CSF1 R antibody, CSF1R antibody, CSF1R_HUMAN antibody, CSFR antibody, EC 2.7.10.1 antibody, FIM 2 antibody, FIM2 antibody, FMS antibody, FMS proto oncogene antibody, FMS protooncogene antibody, HDLS antibody, M-CSF Receptor antibody, M-CSF-R antibody, Macrophage colony stimulating factor 1 receptor antibody, Macrophage colony stimulating factor I receptor antibody, Macrophage colony-stimulating factor 1 receptor antibody, McDonough feline sarcoma viral (v fms) oncogene homolog antibody, MCSFR antibody, Oncogen FMS antibody, Proto-oncogene c-Fms antibody, V-FMS McDonough feline sarcoma viral oncogen homolog, formerly antibody

UniProt: P07333

Pathways: Signalisation RTK, Inositol Metabolic Process, Cell-Cell Junction Organization