PRKAB1 anticorps

N° du produit ABIN7140293

Cet anticorps Souris Monoclonal détecte spécifiquement PRKAB1 dans WB, IHC, ELISA, ICC et IP. Il présente une réactivité envers Humain.

Aperçu rapide pour PRKAB1 anticorps (ABIN7140293)

Antigène: PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PRKAB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunoprecipitation (IP)

Détail du produit anti-PRKAB1 anticorps

Fonction: PRKAB1 Monoclonal Antibody

Réactivité croisée: Singe, Souris, Rat

Purification: Affinity purified

Immunogène: Purified recombinant human AMPK beta 1 protein fragments expressed in E.coli.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified mouse monoclonal antibody in PBS( pH 7.4) containing with 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PRKAB1

Antigène: PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))

Autre désignation: PRKAB1

Sujet:

Background: Non-catalytic subunit of AMP-activated protein kinase (AMPK),an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism.In response to reduction of intracellular ATP levels,AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein,carbohydrate and lipid biosynthesis,as well as cell growth and proliferation.AMPK acts via direct phosphorylation of metabolic enzymes,and by longer-term effects via phosphorylation of transcription regulators.Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton,probably by indirectly activating myosin.Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles,via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1,PRKAG2 or PRKAG3).

Aliases: 1300015D22Rik, 5 AMP activated protein kinase subunit beta 1, 5-AMP-activated protein kinase subunit beta-1, AAKB1_HUMAN, AMP-ACTIVATED PROTEIN KINASE, NONCATALYTIC, BETA-1, AMP-activated, noncatalytic, beta-1, AMPK, AMPK beta 1 chain,

UniProt: Q9Y478

Pathways: AMPK Signaling, L'effet Warburg