FEN1 anticorps (AA 85-383)

N° du produit ABIN7140478

Cet anticorps anti-FEN1 est un anticorps Lapin Polyclonal détectant FEN1 dans WB et ELISA. Adapté pour Arabidopsis thaliana.

Aperçu rapide pour FEN1 anticorps (AA 85-383) (ABIN7140478)

Antigène: FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))

Reactivité: Arabidopsis thaliana

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FEN1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-FEN1 anticorps

Épitope: AA 85-383

Réactivité croisée: Arabidopsis thaliana

Purification: >95%, Protein G purified

Immunogène: Recombinant Arabidopsis thaliana Flap endonuclease 1 protein (85-383AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur FEN1

Antigène: FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))

Autre désignation: FEN1

Sujet:

Background: Structure-specific nuclease with 5\'-flap endonuclease and 5\'-3\' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5\'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5\'-end of a downstream Okazaki fragment. It enters the flap from the 5\'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinicapyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5\'-3\' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.

Aliases: FEN1 antibody, At5g26680 antibody, F21E10.3Flap endonuclease 1 antibody, FEN-1 antibody, EC 3.1.-.- antibody, Flap structure-specific endonuclease 1 antibody

UniProt: O65251

Pathways: Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA