PDK3 anticorps (AA 137-406)

N° du produit ABIN7142007

L’anticorps Lapin Polyclonal anti-PDK3 a été validé pour WB, ELISA et IHC. Il convient pour détecter PDK3 dans des échantillons de Humain.

Aperçu rapide pour PDK3 anticorps (AA 137-406) (ABIN7142007)

Antigène: PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDK3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PDK3 anticorps

Épitope: AA 137-406

Fonction: PDK3 Antibody

Réactivité croisée: Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial protein (137-406AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PDK3

Antigène: PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

Autre désignation: PDK3

Sujet:

Background: Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species.

Aliases: [Pyruvate dehydrogenase [lipoamide] kinase isozyme 3 mitochondrial antibody, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3 antibody, CMTX6 antibody, GS1-358P8.4 antibody, mitochondrial antibody, PDK3 antibody, PDK3_HUMAN antibody, Pyruvate dehydrogenase kinase isoenzyme 3 antibody, Pyruvate dehydrogenase kinase isoform 3 antibody, Pyruvate dehydrogenase kinase isozyme 3 antibody, Pyruvate dehydrogenase lipoamide kinase isozyme 3 mitochondrial antibody

UniProt: Q15120

Pathways: Signalisation PI3K-Akt, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg