14-3-3 sigma/SFN anticorps (AA 1-248)

N° du produit ABIN7142099

Cet anticorps Lapin Polyclonal détecte spécifiquement 14-3-3 sigma/SFN dans WB, IHC, ELISA et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour 14-3-3 sigma/SFN anticorps (AA 1-248) (ABIN7142099)

Antigène: 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp 14-3-3 sigma/SFN est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-14-3-3 sigma/SFN anticorps

Épitope: AA 1-248

Fonction: SFN Antibody

Réactivité croisée: Souris, Rat

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human 14-3-3 protein sigma protein (1-248AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur 14-3-3 sigma/SFN

Antigène: 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

Autre désignation: SFN

Sujet:

Background: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.

Aliases: 14 3 3 protein sigma antibody, 14-3-3 protein sigma antibody, 1433S_HUMAN antibody, Epithelial cell marker protein 1 antibody, Er antibody, HME 1 antibody, HME1 antibody, MGC143283 antibody, Mkrn3 antibody, Mme1 antibody, OTTHUMP00000004242 antibody, RP23 137L22.11 antibody, SFN antibody, SFN protein antibody, Stratifin antibody, YWHAS antibody

UniProt: P31947

Pathways: Signalisation p53, Myometrial Relaxation and Contraction