ARL6 anticorps (AA 1-186)

N° du produit ABIN7143513

L’anticorps Lapin Polyclonal anti-ARL6 a été validé pour IHC et ELISA. Il convient pour détecter ARL6 dans des échantillons de Humain.

Aperçu rapide pour ARL6 anticorps (AA 1-186) (ABIN7143513)

Antigène: ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARL6 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-ARL6 anticorps

Épitope: AA 1-186

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human ADP-ribosylation factor-like protein 6 protein (1-186AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ARL6

Antigène: ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))

Autre désignation: ARL6

Sujet:

Background: Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia (PubMed:20603001). Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia (By similarity). Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation (PubMed:22072986). May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade (PubMed:20207729). Isoform 2 may be required for proper retinal function and organization (By similarity).

Aliases: ADP ribosylation factor like 6 antibody, ADP ribosylation factor like protein 6 antibody, ADP-ribosylation factor-like protein 6 antibody, Arl6 antibody, ARL6_HUMAN antibody, Bardet Biedl syndrome 3 protein antibody, Bardet-Biedl syndrome 3 protein antibody, BBS3 antibody, MGC32934 antibody

UniProt: Q9H0F7