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ARL6 anticorps (AA 1-186)

ARL6 Reactivité: Humain IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7143513
  • Antigène Voir toutes ARL6 Anticorps
    ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))
    Épitope
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-186
    Reactivité
    • 19
    • 3
    • 1
    • 1
    Humain
    Hôte
    • 17
    • 2
    • 1
    Lapin
    Clonalité
    • 19
    • 1
    Polyclonal
    Conjugué
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ARL6 est non-conjugé
    Application
    • 9
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
     Réactivité croisée
    Humain
    Purification
    Antigen Affinity Purified
    Immunogène
    Recombinant Human ADP-ribosylation factor-like protein 6 protein (1-186AA)
    Isotype
    IgG
    Top Product
    Discover our top product ARL6 Anticorps primaire
  • Indications d'application
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))
    Autre désignation
    ARL6 (ARL6 Produits)
    Synonymes
    anticorps BBS3, anticorps RP55, anticorps 1110018H24Rik, anticorps 2210411E14Rik, anticorps zgc:101762, anticorps arl6, anticorps ADP ribosylation factor like GTPase 6, anticorps ADP-ribosylation factor-like 6, anticorps ADP-ribosylation factor like GTPase 6, anticorps ADP-ribosylation factor-like protein 6, anticorps ADP ribosylation factor like GTPase 6 L homeolog, anticorps ARL6, anticorps Arl6, anticorps arl6, anticorps arl-6, anticorps arl6.L
    Sujet

    Background: Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia (PubMed:20603001). Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia (By similarity). Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation (PubMed:22072986). May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade (PubMed:20207729). Isoform 2 may be required for proper retinal function and organization (By similarity).

    Aliases: ADP ribosylation factor like 6 antibody, ADP ribosylation factor like protein 6 antibody, ADP-ribosylation factor-like protein 6 antibody, Arl6 antibody, ARL6_HUMAN antibody, Bardet Biedl syndrome 3 protein antibody, Bardet-Biedl syndrome 3 protein antibody, BBS3 antibody, MGC32934 antibody

    UniProt
    Q9H0F7
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