DDX42 anticorps (AA 519-819)

N° du produit ABIN7144990

Cet anticorps anti-DDX42 est un anticorps Lapin Polyclonal détectant DDX42 dans ELISA, IF et IHC. Adapté pour Humain.

Aperçu rapide pour DDX42 anticorps (AA 519-819) (ABIN7144990)

Antigène: DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDX42 est non-conjugé

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-DDX42 anticorps

Épitope: AA 519-819

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human ATP-dependent RNA helicase DDX42 protein (519-819AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DDX42

Antigène: DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))

Autre désignation: DDX42

Sujet:

Background: ATP-dependent RNA helicase. Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.

Aliases: DDX42ATP-dependent RNA helicase DDX42 antibody, EC 3.6.4.13 antibody, DEAD box protein 42 antibody, RNA helicase-like protein antibody, RHELP antibody, RNA helicase-related protein antibody, RNAHP antibody, SF3b DEAD box protein antibody, Splicing factor 3B-associated 125 kDa protein antibody, SF3b125 antibody

UniProt: Q86XP3