KCTD6 anticorps (AA 1-237) (FITC)
Aperçu rapide pour KCTD6 anticorps (AA 1-237) (FITC) (ABIN7145858)
Antigène
Voir toutes KCTD6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-237
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Fonction
- KCTD6 Antibody, FITC conjugated
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Human BTB/POZ domain-containing protein KCTD6 protein (1-237AA)
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Isotype
- IgG
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anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (AA 1-237) antibody
KCTD6 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (N-Term) antibodyKCTD6 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (N-Term) antibodyKCTD6 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (AA 1-237) antibodyKCTD6 Reactivité: Humain WB Hôte: Souris Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (AA 21-70) antibodyKCTD6 Reactivité: Humain WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (AA 72-121) antibodyKCTD6 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Roussette (Chauve-souris), Poulet, Singe, Porc WB Hôte: Lapin Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (N-Term) antibodyKCTD6 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- KCTD6 (Potassium Channel Tetramerisation Domain Containing 6 (KCTD6))
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Autre désignation
- KCTD6
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Sujet
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Background: Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1, the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1, the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142). Involved in regulating protein levels of ANK1 isoform Mu17 probably implicating CUL3-dependent proteasomal degradation (PubMed:22573887).
Aliases: BTB/POZ domain-containing protein KCTD6 antibody, KCASH3 antibody, kctd6 antibody, KCTD6_HUMAN antibody, MGC27385 antibody, potassium channel tetramerization domain containing 6 antibody
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UniProt
- Q8NC69
Antigène
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