CARD16 anticorps (AA 1-197) (FITC)
Aperçu rapide pour CARD16 anticorps (AA 1-197) (FITC) (ABIN7146913)
Antigène
Voir toutes CARD16 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-197
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Réactivité croisée
- Humain
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Purification
- Antigen Affinity Purified
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Immunogène
- Recombinant Human Caspase recruitment domain-containing protein 16 protein (1-197AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))
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Autre désignation
- CARD16
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Sujet
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Background: Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
Aliases: CAR16_HUMAN antibody, CARD only domain-containing protein 1 antibody, CARD only protein antibody, CARD16 antibody, Caspase recruitment domain family, member 16 antibody, Caspase recruitment domain-containing protein 16 antibody, Caspase-1 dominant-negative inhibitor pseudo-ICE antibody, Caspase-1 inhibitor COP antibody, COP antibody, COP1 antibody, Pseudo interleukin 1 beta converting enzyme antibody, Pseudo interleukin-1 beta converting enzyme antibody, Pseudo interleukin-1beta converting enzyme antibody, PSEUDO-ICE antibody
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UniProt
- Q5EG05
Antigène
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