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CD44 anticorps (AA 21-220)

Name: CD44 anticorps (AA 21-220)
Brand: antibodies-online
SKU: ABIN7147160
Price: 462 EUR
Availability: InStock

Cet anticorps Souris Monoclonal détecte spécifiquement CD44 dans FACS, WB, IHC, ELISA et IF. Il présente une réactivité envers Humain.

Western Blot Positive WB detected in: Hela whole cell lysate, HUVEC whole cell lysate, A549 whole cell lysate, MCF-7 whole cell lysate All lanes: CD44 antibody at 1:1500 Secondary Goat polyclonal to Mouse IgG at 1/10000 dilution Predicted band size: 82, 4, 78, 77, 81, 79, 75, 54,47, 40, 44, 33, 74, 76, 38, 16 kDa Observed band size: 95 kDa (CD44 anticorps (AA 21-220))

Overlay histogram showing Hela cells stained with ABIN7147160 (red line) at 1:200. (CD44 anticorps (AA 21-220))

FACS

Western Blot Positive WB detected in: A549 whole cell lysate All lanes: CD44 antibody at 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000 Secondary Goat polyclonal to Mouse IgG at 1/10000 dilution Predicted band size: 82, 4, 78, 77, 81, 79, 75, 54,47, 40, 44, 33, 74, 76, 38, 16 kDa Observed band size: 95 kDa (CD44 anticorps (AA 21-220))

IHC image of ABIN7147160 diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. (CD44 anticorps (AA 21-220))

IHC

IHC image of ABIN7147160 diluted at 1:100 and staining in paraffin-embedded human skin tissue performed on a Leica BondTM system. (CD44 anticorps (AA 21-220))

IHC

IHC image of ABIN7147160 diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. (CD44 anticorps (AA 21-220))

IHC

Immunofluorescence staining of Hela cells with ABIN7147160 at 1:100, counter-stained with DAPI. (CD44 anticorps (AA 21-220))

Immunofluorescence staining of MCF-7 cells with ABIN7147160 at 1:100, counter-stained with DAPI. (CD44 anticorps (AA 21-220))

8 images

N° du produit ABIN7147160

Aperçu rapide pour CD44 anticorps (AA 21-220) (ABIN7147160)

Antigène

Voir toutes CD44 Anticorps

CD44

Reactivité

Humain

Hôte

Souris

Clonalité

Monoclonal

Conjugué

Cet anticorp CD44 est non-conjugé

Application

Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone

6G2D2

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Épitope
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AA 21-220

Fonction

CD44 Monoclonal Antibody

Purification

Protein G purified

Pureté

>95 %

Immunogène

Recombinant Human CD44 antigen protein (21-220AA)

Isotype

Ig kappa, IgG1
anti-CD44 (CD44) antibody
CD44 Reactivité: Humain, Souris FACS, IHC, ELISA, ICC Hôte: Souris Monoclonal 8E2F3 unconjugated

anti-CD44 (CD44) antibody
KO Validated CD44 Reactivité: Humain WB, IF, IHC (p), IP, IHC (fro), ICC, LCI Hôte: Lapin Polyclonal unconjugated

anti-CD44 (CD44) antibody
CD44 Reactivité: Humain, Chien, Porc FACS, WB, IHC (p), IP Hôte: Souris Monoclonal MEM-263 unconjugated

anti-CD44 (CD44) (AA 148-247) antibody
CD44 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated

anti-CD44 (CD44) (AA 36-194) antibody
CD44 Reactivité: Humain FACS, WB, IHC, ELISA Hôte: Souris Monoclonal 7F4F1 unconjugated

anti-CD44 (CD44) antibody
CD44 Reactivité: Humain FACS, WB, IHC, ELISA, IHC (p), IP, Inhibition Hôte: Souris Monoclonal MEM-85 unconjugated

anti-CD44 (CD44) (AA 21-259) antibody
CD44 Reactivité: Humain, Souris, Rat FACS, WB, IHC, ELISA, IF, IHC (fro), ICC Hôte: Lapin Polyclonal unconjugated

anti-CD44 (CD44) (AA 35-300) antibody
CD44 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated

anti-CD44 (CD44) (AA 1-361) antibody
CD44 Reactivité: Humain WB, IHC (p) Hôte: Souris Polyclonal unconjugated

anti-CD44 (CD44) antibody
CD44 Reactivité: Humain, Babouin, Green Monkey FACS, WB, IHC, IF, Func, StM Hôte: Souris Monoclonal 156-3C11 unconjugated

Indications d'application

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Buffer

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur

ProClin

Précaution d'utilisation

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

-20 °C,-80 °C

Stockage commentaire

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Antigène

CD44

Autre désignation

CD44

Sujet

Background: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9, the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity).
Aliases: CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I, CD44, CD44, LHR, MDU2, MDU3, MIC4

UniProt

P16070

Pathways

Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling