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MAPKAP Kinase 5 anticorps (pSer93)

MAPKAPK5 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN710561
  • Antigène Voir toutes MAPKAP Kinase 5 (MAPKAPK5) Anticorps
    MAPKAP Kinase 5 (MAPKAPK5) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))
    Épitope
    • 27
    • 21
    • 7
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer93
    Reactivité
    • 81
    • 49
    • 32
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 85
    • 9
    • 2
    Lapin
    Clonalité
    • 89
    • 7
    Polyclonal
    Conjugué
    • 40
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp MAPKAP Kinase 5 est non-conjugé
    Application
    • 74
    • 38
    • 26
    • 26
    • 16
    • 11
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Cow,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic phosphopeptide derived from human MAPKAPK5 around the phosphorylation site of Ser93
    Isotype
    IgG
    Top Product
    Discover our top product MAPKAPK5 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    MAPKAP Kinase 5 (MAPKAPK5) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))
    Autre désignation
    MAPKAPK5 (MAPKAPK5 Produits)
    Synonymes
    anticorps MAPKAPK5, anticorps MK5, anticorps PRAK, anticorps MAPKAP-K5, anticorps MK-5, anticorps mitogen-activated protein kinase-activated protein kinase 5, anticorps MAP kinase-activated protein kinase 5, anticorps MAPKAPK5, anticorps mapkapk5, anticorps Mapkapk5
    Sujet

    Synonyms: MAPKAPK5phospho S93, MAP kinase-activated protein kinase 5, MAPKAP kinase 5, MAPKAPK5, mitogen-activated protein kinase-activated protein kinase 5, p38-regulated/activated protein kinase.

    Background: The serine/threonine kinase PRAK is activated in response to cellular stress and proinflammatory cytokines, through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38 alpha, and MAPK11/p38 beta. PRAK has been reported to have a putative tumor suppressor function by mediating senescence upon activation by p38 in response to oncogenic ras. It is thought that phosphorylation of p53 by PRAK following activation of p38 MAPK by ras plays an important role in ras induced senescence and tumor suppression.

    Poids moléculaire
    54kDa
    ID gène
    8550
    Pathways
    Signalisation MAPK
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