Cofilin anticorps (AA 4-144)

N° du produit ABIN7148044

Cet anticorps anti-Cofilin est un anticorps Lapin Polyclonal détectant Cofilin dans IHC, ELISA et IF. Adapté pour Humain.

Aperçu rapide pour Cofilin anticorps (AA 4-144) (ABIN7148044)

Antigène: Cofilin (CFL1) (Cofilin 1 (CFL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cofilin est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Cofilin anticorps

Épitope: AA 4-144

Fonction: CFL1 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Cofilin-1 protein (4-144AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Cofilin

Antigène: Cofilin (CFL1) (Cofilin 1 (CFL1))

Autre désignation: CFL1

Sujet:

Background: Binds to F-actin and exhibits pH -sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed:11812157, PubMed:15580268, PubMed:21834987, PubMed:23633677). Required for neural tube morphogenesis and neural crest cell migration (By similarity).

Aliases: 18 kDa phosphoprotein antibody, CFL 1 antibody, CFL antibody, CFL1 antibody, COF1_HUMAN antibody, Cofilin 1 antibody, Cofilin 1 non muscle antibody, Cofilin antibody, Cofilin non muscle isoform antibody, Cofilin-1 antibody, epididymis secretory protein Li 15 antibody, HEL-S-15 antibody, non-muscle isoform antibody, p18 antibody

UniProt: P23528

Pathways: Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events