COPS8 anticorps (AA 150-198)

N° du produit ABIN7148507

Détail du produit anti-COPS8 anticorps

Antigène: COPS8 (COP9 Signalosome Subunit 8 (COPS8))

Épitope: AA 150-198

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COPS8 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human COP9 signalosome complex subunit 8 protein (150-198AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur COPS8

Antigène: COPS8 (COP9 Signalosome Subunit 8 (COPS8))

Autre désignation: COPS8 (COPS8 Produits)

Synonymes: anticorps COP9, anticorps CSN8, anticorps SGN8, anticorps csn8, anticorps cops8, anticorps MGC76051, anticorps MGC80215, anticorps DDBDRAFT_0167123, anticorps DDBDRAFT_0233107, anticorps DDB_0167123, anticorps DDB_0233107, anticorps zgc:56319, anticorps zgc:86840, anticorps MGC86182, anticorps 9430009J09Rik, anticorps AA408242, anticorps Csn8, anticorps Sgn8, anticorps CONSTITUTIVE PHOTOMORPHOGENIC 9, anticorps COP9 SIGNALOSOME SUBUNIT 8, anticorps DL3095C, anticorps EMB143, anticorps EMBRYO DEFECTIVE 143, anticorps FCAALL.131, anticorps FUS7, anticorps FUSCA 7, anticorps FUSCA PROTEIN FUS7, anticorps CG13383, anticorps CG33297, anticorps CG42522, anticorps CH8, anticorps Dch8, anticorps Dmel\\CG42522, anticorps Dmel_CG13383, anticorps l(2)SH1829, anticorps l(2)SH2 1829, anticorps COP9 signalosome subunit 8, anticorps COP9 signalosome subunit 8 S homeolog, anticorps COP9 signalosome complex subunit 8, anticorps COP9 signalosome subunit 8 L homeolog, anticorps COP9 signalosome, subunit CSN8, anticorps COPS8, anticorps Cops8, anticorps cops8, anticorps cops8.S, anticorps CSN8, anticorps csn8, anticorps cops8.L, anticorps COP9

Sujet:

Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

Aliases: COP9 homolog antibody, COP9 signalosome complex subunit 8 antibody, COP9 signalosome subunit 8 antibody, Cops8 antibody, CSN8 antibody, CSN8_HUMAN antibody, hCOP9 antibody, JAB1 containing signalosome subunit 8 antibody, JAB1-containing signalosome subunit 8 antibody, SGN8 antibody, Signalosome subunit 8 antibody

UniProt: Q99627

Pathways: Cycle Cellulaire