DKK2 anticorps (AA 34-259) (FITC)
Aperçu rapide pour DKK2 anticorps (AA 34-259) (FITC) (ABIN7149884)
Antigène
Voir toutes DKK2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 34-259
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human Dickkopf-related protein 2 protein (34-259AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DKK2 (Dickkopf 2 Homolog (DKK2))
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Autre désignation
- DKK2
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Sujet
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Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Aliases: Dickkopf 2 antibody, Dickkopf gene 2 antibody, Dickkopf homolog 2 antibody, Dickkopf related protein 2 antibody, Dickkopf WNT signaling pathway inhibitor 2 antibody, Dickkopf-2 antibody, Dickkopf-related protein 2 antibody, Dickkopf2 antibody, DKK 2 antibody, Dkk-2 antibody, Dkk2 antibody, DKK2_HUMAN antibody, hDkk 2 antibody, hDkk-2 antibody, hDkk2 antibody
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UniProt
- Q9UBU2
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Pathways
- Signalisation WNT
Antigène
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