Ephrin B3 anticorps (AA 28-226)
Aperçu rapide pour Ephrin B3 anticorps (AA 28-226) (ABIN7151880)
Antigène
Voir toutes Ephrin B3 (EFNB3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 28-226
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Fonction
- EFNB3 Antibody
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Purification
- Antigen Affinity Purified
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Immunogène
- Recombinant Human Ephrin-B3 protein (28-226AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Ephrin B3 (EFNB3)
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Autre désignation
- EFNB3
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Sujet
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Background: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity).
Aliases: EFL 6 antibody, EFL6 antibody, EFNB 3 antibody, Efnb3 antibody, EFNB3_HUMAN antibody, EPH related receptor transmembrane ligand ELK L3 antibody, EPH related receptor transmembrane ligand ELKL3 antibody, EPH related receptor tyrosine kinase ligand 8 antibody, EPH-related receptor transmembrane ligand ELK-L3 antibody, EPH-related receptor tyrosine kinase ligand 8 antibody, Ephrin B3 antibody, Ephrin-B3 antibody, EphrinB3 antibody, EPLG 8 antibody, EPLG8 antibody, LERK 8 antibody, LERK-8 antibody, LERK8 antibody
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UniProt
- Q15768
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Pathways
- Signalisation RTK
Antigène
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