Exonuclease 1 anticorps (AA 301-600) (FITC)
Aperçu rapide pour Exonuclease 1 anticorps (AA 301-600) (FITC) (ABIN7152267)
Antigène
Voir toutes Exonuclease 1 (EXO1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 301-600
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Fonction
- EXO1 Antibody, FITC conjugated
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Human Exonuclease 1 protein (301-600AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Exonuclease 1 (EXO1)
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Autre désignation
- EXO1
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Sujet
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Background: 5\'->3\' double-stranded DNA exonuclease which may also possess a cryptic 3\'->5\' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5\' or 3\' to the mismatch. Also exhibits endonuclease activity against 5\'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5\'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.
Aliases: exo1 antibody, EXO1_HUMAN antibody, ExoI antibody, Exonuclease 1 antibody, Exonuclease I antibody, Exonuclease1 antibody, HEX1 antibody, hExo I antibody, hExo1 antibody, hExoI antibody, Rad2 nuclease family member homolog of S. cerevisiae exonuclease 1 antibody
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UniProt
- Q9UQ84
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Pathways
- Réparation de l'ADN, Production of Molecular Mediator of Immune Response
Antigène
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