FZD7 anticorps (AA 161-239)

N° du produit ABIN7153189

Cet anticorps anti-FZD7 est un anticorps Lapin Polyclonal détectant FZD7 dans WB, ELISA et IHC. Adapté pour Humain.

Aperçu rapide pour FZD7 anticorps (AA 161-239) (ABIN7153189)

Antigène: FZD7 (Frizzled Family Receptor 7 (FZD7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FZD7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-FZD7 anticorps

Épitope: AA 161-239

Fonction: FZD7 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Frizzled-7 protein (161-239AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur FZD7

Antigène: FZD7 (Frizzled Family Receptor 7 (FZD7))

Autre désignation: FZD7

Sujet:

Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

Aliases: Frizzled 7, seven transmembrane spanning receptor antibody, frizzled class receptor 7 antibody, Frizzled drosophila homolog of 7 antibody, Frizzled family receptor 7 antibody, Frizzled homolog 7 antibody, Frizzled-7 antibody, Frizzled7 antibody, Fz 7 antibody, Fz-7 antibody, Fz7 antibody, FZD 7 antibody, FZD7 antibody, FZD7_HUMAN antibody, FzE 3 antibody, FzE3 antibody, hFz 7 antibody, hFz7 antibody, Homolog of Drosophila Frizzled 7 antibody, OTTHUMP00000163742 antibody

UniProt: O75084

Pathways: Signalisation WNT, Stem Cell Maintenance