FZD9 anticorps (AA 23-229) (Biotin)
Aperçu rapide pour FZD9 anticorps (AA 23-229) (Biotin) (ABIN7153198)
Antigène
Voir toutes FZD9 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 23-229
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Fonction
- FZD9 Antibody, Biotin conjugated
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Human Frizzled-9 protein (23-229AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FZD9 (Frizzled Family Receptor 9 (FZD9))
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Autre désignation
- FZD9
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Sujet
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Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
Aliases: CD 349 antibody, CD 349 antigen antibody, CD349 antibody, Frizzled Drosophila homolog of 3 antibody, Frizzled homolog 9 (Drosophila) antibody, Frizzled homolog 9 antibody, Frizzled-9 antibody, Fz 9 antibody, Fz-9 antibody, FZD 3 antibody, Fzd 9 antibody, FZD3 antibody, FZD3-PEN antibody, FZD9 antibody, FZD9_HUMAN antibody, FzE6 antibody, hFz9 antibody, mfz9 antibody, Xfz9 antibody
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UniProt
- O00144
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Pathways
- Signalisation WNT
Antigène
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