GRK6 anticorps (AA 1-170)

N° du produit ABIN7153301

Cet anticorps Lapin Polyclonal détecte spécifiquement GRK6 dans ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour GRK6 anticorps (AA 1-170) (ABIN7153301)

Antigène: GRK6 (G Protein-Coupled Receptor Kinase 6 (GRK6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRK6 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-GRK6 anticorps

Épitope: AA 1-170

Fonction: GRK6 Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human G protein-coupled receptor kinase 6 protein (1-170AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GRK6

Antigène: GRK6 (G Protein-Coupled Receptor Kinase 6 (GRK6))

Autre désignation: GRK6

Sujet:

Background: Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).

Aliases: FLJ32135 antibody, G protein coupled receptor kinase 6 antibody, G protein coupled receptor kinase GRK6 antibody, G protein-coupled receptor kinase 6 antibody, G protein-coupled receptor kinase GRK6 antibody, Gprk6 antibody, Grk6 antibody, GRK6_HUMAN antibody

UniProt: P43250

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Negative Regulation of Transporter Activity