GANP anticorps (AA 292-435) (FITC)
Aperçu rapide pour GANP anticorps (AA 292-435) (FITC) (ABIN7153845)
Antigène
Voir toutes GANP (MCM3AP) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 292-435
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human Germinal-center associated nuclear protein (292-435AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GANP (MCM3AP) (Minichromosome Maintenance Complex Component 3 Associated Protein (MCM3AP))
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Autre désignation
- MCM3AP
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Sujet
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Background: Isoform GANP: Essential for the generation of high-affinity B-cells against T-cell-dependent antigens by affecting somatic hypermutation at the IgV-regions. May have stimulation-dependent DNA primase activity that would generate extra RNA primers in very rapidely proliferating cells and would support clonal expansion of differentiating B-cells (By similarity). Involved in the nuclear export of poly(A)-containing mRNAs by acting as a scaffold for the TREX-2 complex. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
Aliases: 80 kDa MCM3 associated protein antibody, 80 kDa MCM3-associated protein antibody, FLJ44336 antibody, FLJ45306 antibody, Germinal center associated nuclear protein antibody, KIAA0572 antibody, MAP80 antibody, MCM3 import protein antibody, MCM3 minichromosome maintenance deficient 3 associated protein antibody, MCM3A antibody, MCM3A_HUMAN antibody, Mcm3ap antibody, Minichromosome maintenance complex component 3 associated protein antibody, Minichromosome maintenance deficient 3 associated protein antibody, Minichromosome maintenance protein 3 associated protein antibody, Protein GANP antibody, SAC3 antibody
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UniProt
- O60318
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Pathways
- Protein targeting to Nucleus
Antigène
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