GCK anticorps (AA 1-300)

N° du produit ABIN7153890

Détail du produit anti-GCK anticorps

Antigène: GCK (Glucokinase (Hexokinase 4) (GCK))

Épitope: AA 1-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCK est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Glucokinase protein (1-300AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GCK

Antigène: GCK (Glucokinase (Hexokinase 4) (GCK))

Autre désignation: GCK (GCK Produits)

Synonymes: anticorps FGQTL3, anticorps GK, anticorps GLK, anticorps HHF3, anticorps HK4, anticorps HKIV, anticorps HXKP, anticorps LGLK, anticorps MODY2, anticorps Gk, anticorps Gls006, anticorps GCK, anticorps BA4487, anticorps glk, anticorps hk4, anticorps hhf3, anticorps hkiv, anticorps hxkp, anticorps gck-A, anticorps mody2, anticorps glucokinase, anticorps GLUKA, anticorps RNGK2, anticorps glucokinase, anticorps glucokinase (hexokinase 4) L homeolog, anticorps glucokinase (hexokinase 4), anticorps GCK, anticorps Gck, anticorps glcK, anticorps Bphyt_1025, anticorps Halhy_6548, anticorps gk, anticorps gck.L, anticorps gck

Sujet:

Background: Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.

Aliases: ATP:D-hexose 6-phosphotransferase antibody, FGQTL3 antibody, GCK antibody, GK antibody, GLK antibody, Glucokinase antibody, Hexokinase D pancreatic isozyme antibody, Hexokinase type IV antibody, Hexokinase-4 antibody, Hexokinase-D antibody, HHF3 antibody, HK IV antibody, HK4 antibody, HKIV antibody, HXK4_HUMAN antibody, HXKP antibody, LGLK antibody, MODY2 antibody

UniProt: P35557

Pathways: Signalisation MAPK, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process