PRKAA1 anticorps (pThr198)

N° du produit ABIN711236

L’anticorps Lapin Polyclonal anti-PRKAA1 a été validé pour WB, ELISA, IHC (p), FACS, IF (cc), IF (p) et IHC (fro). Il convient pour détecter PRKAA1 dans des échantillons de Humain, Souris, Rat et Chien.

Aperçu rapide pour PRKAA1 anticorps (pThr198) (ABIN711236)

Antigène: PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKAA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-PRKAA1 anticorps

Épitope: pThr198

Réactivité croisée: Chien, Humain, Souris, Rat

Homologie: Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human PRKAA1 around the phosphorylation site of Thr198

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PRKAA1

Antigène: PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))

Autre désignation: AMPK alpha-1

Sujet:

Synonyms: AMPK alpha 1 + AMPK alpha 2 phospho S485 + S491, PRKAA1phospho S79, 5 AMP activated protein kinase alpha 1catalytic subunit, 5 AMP activated protein kinase catalytic alpha 1 chain, 5' AMP activated protein kinase catalytic subunit alpha 1, AAPK1,acetyl CoA carboxylase kinase,AI194361 antibody AI450832 ,AL024255 ,AMP -activate kinase alpha 1 subunit,AMP-activated protein kinase, catalytic, alpha -1,AMPK 1,AMPK alpha 1 chain,AMPK antibody AMPK1, AMPKa1,AMPKalpha1,C130083N04Rik,cb116 antibody EC 2.7.11.1, HMG CoA reductase kinase,hormone sensitive lipase kinase,im:7154392 antibody kinase AMPK alpha1 ,MGC33776,MGC57364 antibody PRKAA 1,PRKAA1,Protein kinase AMP activated alpha 1 catalytic subunit, SNF1-like protein AMPK,wu:fa94C10.

Background: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq].

Poids moléculaire: 63kDa

ID gène: 5562

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg