SETD7 anticorps (AA 1-218) (Biotin)

N° du produit ABIN7155518

Détail du produit anti-SETD7 anticorps (Biotin)

Antigène: SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))

Épitope: AA 1-218

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SETD7 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Histone-lysine N-methyltransferase SETD7 protein (1-218AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SETD7

Antigène: SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))

Autre désignation: SETD7 (SETD7 Produits)

Synonymes: anticorps KMT7, anticorps SET7, anticorps SET7/9, anticorps SET9, anticorps set7, anticorps zgc:101860, anticorps zgc:92330, anticorps 1600028F23Rik, anticorps H3K4MT, anticorps Set7, anticorps Set7/9, anticorps mKIAA1717, anticorps SET domain containing lysine methyltransferase 7, anticorps SET domain containing (lysine methyltransferase) 7, anticorps SETD7, anticorps setd7, anticorps Setd7

Sujet:

Background: Histone methyltransferase that specifically monomethylates \\\'Lys-4\\\' of histone H3. H3 \\\'Lys-4\\\' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates \\\'Lys-189\\\' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates \\\'Lys-372\\\' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.

Aliases: FLJ21193 antibody, H3 K4 HMTase antibody, H3-K4-HMTase SETD7 antibody, H4 lysine 4 specific antibody, Histone H3 K4 methyltransferase antibody, Histone H3 lysine 4 specific methyltransferase antibody, Histone H3-K4 methyltransferase SETD7 antibody, Histone H4 K4 methyltransferase antibody, Histone lysine N methyltransferase antibody, Histone lysine N methyltransferase H3 lysine 4 specific SET7 antibody, Histone-lysine N-methyltransferase SETD7 antibody, KIAA1717 antibody, KMT7 antibody, Lysine methyltransferase antibody, Lysine N-methyltransferase 7 antibody, OTTHUMP00000164543 antibody, OTTHUMP00000220049 antibody, SET 7 antibody, SET 7/9 antibody, SET 9 antibody, SET D7 antibody, SET domain containing (lysine methyltransferase) 7 antibody, SET domain containing protein 7 antibody, SET domain containing protein 8 antibody, SET domain-containing protein 7 antibody, SET7 antibody, SET7/9 antibody, SET9 antibody, Setd7 antibody, SETD7_HUMAN antibody

UniProt: Q8WTS6