INSIG1 anticorps (AA 1-87) (HRP)
Aperçu rapide pour INSIG1 anticorps (AA 1-87) (HRP) (ABIN7156351)
Antigène
Voir toutes INSIG1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-87
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human Insulin-induced gene 1 protein (1-87AA)
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Isotype
- IgG
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anti-Insulin Induced Gene 1 (INSIG1) (AA 1-87) antibody
INSIG1 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Internal Region) antibodyINSIG1 Reactivité: Humain, Souris WB, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 36-63), (N-Term) antibodyINSIG1 Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB21689 unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 63-112) antibodyINSIG1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chévre, Cheval, Lapin, Chien, Cobaye, Porc, Singe, Hamster, Xenopus laevis, Roussette (Chauve-souris), Poulet WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibodyINSIG1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chévre, Cheval, Lapin, Chien, Cobaye, Mouton, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (C-Term) antibodyINSIG1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (AA 71-120) antibodyINSIG1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chévre, Cheval, Lapin, Mouton, Porc, Hamster, Xenopus laevis WB Hôte: Lapin Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (C-Term) antibodyINSIG1 Reactivité: Humain, Singe WB Hôte: Lapin Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibodyINSIG1 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
anti-Insulin Induced Gene 1 (INSIG1) (Middle Region) antibodyINSIG1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chévre, Cheval, Lapin, Chien, Cobaye, Mouton, Porc, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- INSIG1 (Insulin Induced Gene 1 (INSIG1))
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Autre désignation
- INSIG1
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Sujet
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Background: Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Initiates the sterol-mediated ubiquitin-mediated endoplasmic reticulum-associated degradation (ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligase, AMFR/gp78. May play a role in growth and differentiation of tissues involved in metabolic control. May play a regulatory role during G0/G1 transition of cell growth.
Aliases: CL 6 antibody, CL6 antibody, INSI1_HUMAN antibody, INSIG 1 antibody, INSIG 1 membrane protein antibody, INSIG-1 antibody, insig1 antibody, INSIG1 membrane protein antibody, Insulin induced gene 1 antibody, Insulin induced gene 1 protein antibody, Insulin-induced gene 1 protein antibody, MGC1405 antibody
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UniProt
- O15503
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Pathways
- ER-Nucleus Signaling
Antigène
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