Inversin anticorps (AA 1-101) (HRP)

N° du produit ABIN7157011

Cet anticorps anti-Inversin est un anticorps Lapin Polyclonal détectant Inversin dans ELISA. Adapté pour Humain.

Aperçu rapide pour Inversin anticorps (AA 1-101) (HRP) (ABIN7157011)

Antigène: Inversin (INVS)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Inversin est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-Inversin anticorps (HRP)

Épitope: AA 1-101

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Inversin protein (1-101AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Inversin

Antigène: Inversin (INVS)

Autre désignation: INVS

Sujet:

Background: Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled (DVL1) for degradation by the ubiquitin-proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling. Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity).

Aliases: INVS antibody, INV antibody, NPHP2 antibody, Inversin antibody, Inversion of embryo turning homolog antibody, Nephrocystin-2 antibody

UniProt: Q9Y283