JUP anticorps (AA 1-131)

N° du produit ABIN7157158

Cet anticorps anti-JUP est un anticorps Lapin Polyclonal détectant JUP dans WB, IHC et ELISA. Adapté pour Humain.

Aperçu rapide pour JUP anticorps (AA 1-131) (ABIN7157158)

Antigène: JUP (Junction Plakoglobin (JUP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JUP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-JUP anticorps

Épitope: AA 1-131

Fonction: JUP Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Junction plakoglobin protein (1-131AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur JUP

Antigène: JUP (Junction Plakoglobin (JUP))

Autre désignation: JUP

Sujet:

Background: Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).

Aliases: ARVD 12 antibody, ARVD12 antibody, Catenin (cadherin associated protein), gamma 80 kDa antibody, catenin (cadherin-associated protein) gamma (80kD) antibody, Catenin gamma antibody, CTNNG antibody, Desmoplakin 3 antibody, Desmoplakin III antibody, Desmoplakin-3 antibody, Desmoplakin3 antibody, DesmoplakinIII antibody, DP 3 antibody, DP III antibody, DP3 antibody, DPIII antibody, gamma catenin antibody, Junction plakoglobin antibody, JUP antibody, OTTHUMP00000164732 antibody, OTTHUMP00000164735 antibody, OTTHUMP00000164738 antibody, PDGB antibody, PKGB antibody, PLAK_HUMAN antibody, PLAKOGLOBIN antibody

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location