Kallikrein 6 anticorps (AA 22-244)

N° du produit ABIN7157217

Détail du produit anti-Kallikrein 6 anticorps

Antigène: Kallikrein 6 (KLK6)

Épitope: AA 22-244

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Kallikrein-6 protein (22-244AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Kallikrein 6

Antigène: Kallikrein 6 (KLK6)

Autre désignation: KLK6 (KLK6 Produits)

Synonymes: anticorps Bssp, anticorps Klk7, anticorps PRSS18, anticorps PRSS9, anticorps SP59, anticorps hK6, anticorps Prss9, anticorps AI849898, anticorps BSP, anticorps Klk29, anticorps MSP, anticorps Prss18, anticorps neurosin, anticorps kallikrein related peptidase 6, anticorps kallikrein related-peptidase 6, anticorps kallikrein-6, anticorps KLK6, anticorps Klk6, anticorps LOC100716801

Sujet:

Background: Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis.

Aliases: Bssp antibody, hK 6 antibody, hK6 antibody, Kallikrein 6 precursor antibody, Kallikrein related peptidase 6 antibody, Kallikrein-6 antibody, Kallikrein6 antibody, KLK 6 antibody, Klk 7 antibody, KLK 9 antibody, Klk29 antibody, Klk6 antibody, KLK6_HUMAN antibody, Klk7 antibody, KLK9 antibody, MGC9355 antibody, mGK 1 antibody, mGK1 antibody, MSP antibody, Neurosin antibody, Protease M antibody, Protease serine 18 antibody, Protease serine 9 antibody, PRSS 18 antibody, PRSS 9 antibody, PRSS18 antibody, PRSS9 antibody, Serine protease 18 antibody, Serine protease 9 antibody, SP 59 antibody, SP59 antibody, Tissue kallikrein antibody, TK antibody, Zyme antibody

UniProt: Q92876

Pathways: Système du Complément, Regulation of G-Protein Coupled Receptor Protein Signaling