KIDINS220 anticorps (AA 1077-1370) (Biotin)

N° du produit ABIN7157551

Cet anticorps anti-KIDINS220 est un anticorps Lapin Polyclonal détectant KIDINS220 dans ELISA. Adapté pour Humain.

Aperçu rapide pour KIDINS220 anticorps (AA 1077-1370) (Biotin) (ABIN7157551)

Antigène: KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIDINS220 est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-KIDINS220 anticorps (Biotin)

Épitope: AA 1077-1370

Fonction: KIDINS220 Antibody, Biotin conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Kinase D-interacting substrate of 220 kDa protein (1077-1370AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KIDINS220

Antigène: KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))

Autre désignation: KIDINS220

Sujet:

Background: Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.

Aliases: Ankyrin repeat-rich membrane-spanning protein antibody, arms antibody, KDIS_HUMAN antibody, kidins220 antibody, Kinase D interacting substance of 220 kDa antibody, Kinase D-interacting substrate of 220 kDa antibody, rgd 619949 antibody

UniProt: Q9ULH0